Learn about Bioneer's FAST Automated cfDNA extraction/Bisulfite Conversion solution for liquid biopsy. Using 2-3ml of whole blood, our system will run cfDNA extraction and bisulfite conversion in 2.5 hours to quickly run methylation analysis.
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Principles
- Bisulfite conversion is the most commonly used tool
for the methylation states of individual cytosines in DNA.
- Bisulfite treatment converts unmethylated cytosines
to uracils and leaves 5 methylcytosines unchanged.
- High Extraction and conversion efficiency with reproducible results
- Much faster runtime than traditional methods: 2.5hr
- Prefilled cartridge system for efficient and reproducible results
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General Process of Bisulfite Conversion
- General bisulfite conversion include complex steps deamination, binding, desulfonation, washing, and elution.
- It requires more than hours and it sis challenging to treat several samples at once in an elaborate way
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| Bisulfite conversion: |
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