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GPScreen

Bioneer's unique Drug Target & Toxicity Identification Services from Bioneer

An Innovative Technology for Drug Target Identification using Drug-induced Haploinsufficiency (DIH) in the World’s First Fission Yeast S. pombe Genome-wide Heterozygous Deletion Mutant Library

Overview
GPScreen™ Services
Literature/Support
Ordering Information

Ⅰ. Outline of GPScreen™ Service Process

This service was designed to meet your specific needs fast (results in only 2-3 weeks) at extremely attractive prices. GPScreen™ services is provided with not only genome-wide screening (using 4840 full mutant strains) or as essential gene screening (using 1259 essential gene mutant strains). Furthermore, we can also provide other screening services on specified functional gene groups which are involved in various signaling pathways and/or disease areas (e.g. Cell cycle regulation/cancers) in accordance with your specific needs: By screening only a specified functional subset of the library you can use this service at a reduced price as described below.






Ⅱ. GPScreen™ Service

GPScreen™ Service provides various screening services to meet the specific needs of customers. Therefore, you can make the best choice among the various services below. After considering the issues and problems of your drug candidates, choose any service you need.


1) Primary Test Service for Determination of Growth-inhibitory Activity (GI50) in Wild Type S. pombe

Primary Test Service will be performed to all compounds requested in advance of GPScreen™

Cat.No. Primary Test Service Cell Type Price
GPS-00   Primary Test Service in Wild Type S. pombe SP286 $200.0 /
Compound

* Price of primary test will be dramatically discounted when the number of compounds is ≥ 2.


2) GPScreen™ Service using S. pombe Genome-wide Mutant Set

Cat.No. Full Screening Service No. of Genes Price
GPS-01-GW   S. pombe Genome-wide Heterozygous Deletion Mutant Screening Service 4840 Inquire


3) GPScreen™ Service using S. pombe Essential gene Mutant Set

Cat.No. Essential Gene Screening Service No. of Genes Price
GPS-02-ESS   S. pombe Essential Gene Heterozygous Deletion Mutant Screening Service 1259 Inquire


4) GPScreen™ Service using KOG analysis-based Functional Group Subsets

Cat.No. Functional Group-based Subset Services No. of Genes Price
   INFORMATION STORAGE AND PROCESSING
GPS-03K-A   A: RNA processing and modification Screening Service 210 Inquire
GPS-03K-B   B: Chromatin structure and dynamics Screening Service 97 Inquire
GPS-03K-J   J: Translation, ribosomal structure and biosis Screening Service 378 Inquire
GPS-03K-K   K: Transcription Screening Service 239 Inquire
GPS-03K-L   L: Replication, recombination and repair Screening Service 180 Inquire
   CELLULAR PROCESSES AND SIGNALING
GPS-03K-D   D: Cell cycle control, cell division, chromosome partitioning Screening Service 183 Inquire
GPS-03K-M   M: Cell wall/membrane/envelope biosis Screening Service 48 Inquire
GPS-03K-N   N: Cell motility Service 2 Inquire
GPS-03K-O   O: Posttranslational modification, protein turnover, chaperones Screening Service 396 Inquire
GPS-03K-T   T: Signal transduction mechanisms Screening Service 285 Inquire
GPS-03K-U   U: Intracellular trafficking, secretion, and vesicular transport Screening Service 292 Inquire
GPS-03K-V   V: Defense mechanisms Screening Service 21 Inquire
GPS-03K-W   W: Extracellular structures Screening Service 5 Inquire
GPS-03K-Y   Y: Nuclear structure Screening Service 31 Inquire
GPS-03K-Z   Z: Cytoskeleton Screening Service 109 Inquire
   METABOLISM
GPS-03K-E   E: Amino acid transport and metabolism Screening Service 187 Inquire
GPS-03K-F   F: Nucleotide transport and metabolism Screening Service 66 Inquire
GPS-03K-G   G: Carbohydrate transport and metabolism Screening Service 142 Inquire
GPS-03K-H   H: Coenzyme transport and metabolism Screening Service 79 Inquire
GPS-03K-I   I: Lipid transport and metabolism Screening Service 118 Inquire
GPS-03K-C   C: Energy production and conversion Screening Service 163 Inquire
GPS-03K-P   P: Inorganic ion transport and metabolism Screening Service 82 Inquire
GPS-03K-Q   Q: Secondary metabolites biosynthesis, transport and catabolism Screening Service 48 Inquire
    POORLY CHARACTERIZED
GPS-03K-R   R: General function prediction only Screening Service 551 Inquire
GPS-03K-S   S: Function unknown Screening Service 284 Inquire


5) GPScreen™ Service using Human Disease-related Subsets

Cat.No. Human Disease-related Subset Services No. of Genes Price
GPS-04H-A   Cell Cycle Regulator Screening Service 321 Inquire
GPS-04H-B   DNA Damage Repair Screening Service 376 Inquire
GPS-04H-C   Cytokinesis Screening Service 124 Inquire
GPS-04H-D   Chromatin Remodeling Screening Service 257 Inquire
GPS-04H-E   Histone Modification Screening Service 63 Inquire
GPS-04H-F   Protein Kinase Screening Service 223 Inquire
GPS-04H-G   GTPase Proteins Screening Service 90 Inquire
GPS-04H-H   ABC Transporter Screening Service 31 Inquire
GPS-04H-I   Transcription Factor Screening Service 362 Inquire
GPS-04H-J   Neurological Disease Screening Service 19 Inquire


GPScreenTM Custom service is now waiting for you.
Please let us (order.usa@bioneer.us.com) know the details about your compounds/ candidate drugs, so that we can provide you with a more accurate quotations and timeline estimate. The service price may vary depending on the number of your compounds requested.

©2010 Bioneer Corporation