siRNA - Custom siRNA Synthesis

CUSTOM SIRNA SYNTHESIS

► Custom RNA Synthesis

► Modification for Custom RNA

siRNA

Control siRNAs
AccuTarget Control siRNA

Custom siRNA
AccuTarget Custom siRNA

Custom siRNA Synthesis

Overview

Technical/Specs

Literature/Support

Search and Order

Let Bioneer design your siRNA with Turbo si-Designer, or use the form below to create your own. Up to 30-mer siRNA, including a choice of 32 different 3' overhangs and/or various modifications, can be ordered. Each siRNA synthesized by Bioneer is purified to near HPLC purity utilizing the company's proprietary BioRP purification system. For higher purity, HPLC is offered at an additional charge. The siRNA is supplied lyophilized and ready-to-use for your convenience.

Each siRNA is quality controlled by MALDI-TOF mass spectrometry to guarantee highest quality and analyzed by PAGE to confirm its duplex structure. Bioneer offers 6 different 5' modifications: Fluorescein, Phosphorylation, Biotin ,Amine and Thiol. Bioneer also offers 6 different 3' modifications: Fluorescein, Phosphorylation, Biotin, Amine, TAMRA and Dabcyl. 6 internal modifications are also available: DNA, 2'-O-Me, 2'-FU, 2'-FC, Inosine and Deoxy-base. All Bioneer's siRNA products are manufactured in a state-of-the-art clean room.

Please fill out the required information for your custom siRNA(s) to see a quote on your order.

siRNA Name

(Max : char.60)

Guarantee
(nmole)

Purification

Annealing Service
(Add $0)

TARGET SEQUENCE

Inputed Target Sequence


Sense	5'	3'
AntiSense	5'	3'
Base seq. length:

Mods/Extra Price :
Base Price :
Annealing Price :
Total Price :

Guaranteed Yield	Purification	Price(US$)
10 nmole	BioRP	189.00
20 nmole		241.50
50 nmole		367.50
100 nmole		430.50
10 nmole	HPLC	315.00
20 nmole		430.00
50 nmole		525.00
100 nmole		567.00

*DSR is only available up to 30 mer. For Double Strand RNA over 30 bases, please select Single Strand RNA.

Please input your sequence below (up to 30 mers including overhang)

Modification

Modification

antisense 5'

Auto. AntiSequence

Product Name	Position	price (US $) / Synthesis Scale (nmole)
Product Name	Position	10 nmole	20 nmole	50 nmole	100 nmole	Set-up Charge
18 atom spacer	3'	65.00	72.00	78.00	104.00
	int	65.00	72.00	78.00	104.00
	5'	65.00	72.00	78.00	104.00
2',3'-ddA	3'
	int
	5'	234.00	257.00	286.00	429.00	Less than 3 (Set-up Charge:175.00)
2',3'-ddC	3'	163.00	179.00	195.00	286.00	Less than 3 (Set-up Charge:250.00)
	int
	5'	234.00	257.00	286.00	429.00	Less than 3 (Set-up Charge:175.00)
2',3'-ddG	3'
	int
	5'	234.00	257.00	286.00	429.00	Less than 3 (Set-up Charge:300.00)
2',3'-ddT	3'
	int
	5'	234.00	257.00	286.00	429.00	Less than 3 (Set-up Charge:175.00)
2,6-Diaminopurine	3'	410.00	450.00	455.00	715.00	Less than 3 (Set-up Charge:175.00)
	int	410.00	450.00	455.00	715.00	Less than 3 (Set-up Charge:175.00)
	5'	410.00	450.00	455.00	715.00	Less than 3 (Set-up Charge:175.00)
2-Aminopurine	3'	410.00	450.00	455.00	715.00	Less than 3 (Set-up Charge:175.00)
	int	410.00	450.00	455.00	715.00	Less than 3 (Set-up Charge:175.00)
	5'	410.00	450.00	455.00	715.00	Less than 3 (Set-up Charge:175.00)
2'-F-rA	3'	65.00	72.00	98.00	163.00	Less than 3 (Set-up Charge:175.00)
	int	65.00	72.00	98.00	163.00	Less than 3 (Set-up Charge:175.00)
	5'	65.00	72.00	98.00	163.00	Less than 3 (Set-up Charge:175.00)
2'-F-rC	3'	65.00	72.00	98.00	163.00	Less than 3 (Set-up Charge:175.00)
	int	65.00	72.00	98.00	163.00	Less than 3 (Set-up Charge:175.00)
	5'	65.00	72.00	98.00	163.00	Less than 3 (Set-up Charge:175.00)
2'-F-rG	3'	65.00	72.00	98.00	163.00	Less than 3 (Set-up Charge:175.00)
	int	65.00	72.00	98.00	163.00	Less than 3 (Set-up Charge:175.00)
	5'	65.00	72.00	98.00	163.00	Less than 3 (Set-up Charge:175.00)
2'-F-rU	3'	65.00	72.00	98.00	163.00	Less than 3 (Set-up Charge:175.00)
	int	65.00	72.00	98.00	163.00	Less than 3 (Set-up Charge:175.00)
	5'	65.00	72.00	98.00	163.00	Less than 3 (Set-up Charge:175.00)
2'-MOE (A)	3'	26.00	29.00	33.00	59.00
	int	26.00	29.00	33.00	59.00
	5'	26.00	29.00	33.00	59.00
2'-MOE (G)	3'	26.00	29.00	33.00	59.00
	int	26.00	29.00	33.00	59.00
	5'	26.00	29.00	33.00	59.00
2'-MOE (U)	3'	26.00	29.00	33.00	59.00
	int	26.00	29.00	33.00	59.00
	5'	26.00	29.00	33.00	59.00
2'-MOE 5-Methyl(C)	3'	26.00	29.00	33.00	59.00
	int	26.00	29.00	33.00	59.00
	5'	26.00	29.00	33.00	59.00
2'-O-Methyl(A)	3'	12.00	13.00	16.00	23.00
	int	12.00	13.00	16.00	23.00
	5'	12.00	13.00	16.00	23.00
2'-O-Methyl(C)	3'	12.00	13.00	16.00	23.00
	int	12.00	13.00	16.00	23.00
	5'	12.00	13.00	16.00	23.00
2'-O-Methyl(G)	3'	12.00	13.00	16.00	23.00
	int	12.00	13.00	16.00	23.00
	5'	12.00	13.00	16.00	23.00
2'-O-Methyl(U)	3'	12.00	13.00	16.00	23.00
	int	12.00	13.00	16.00	23.00
	5'	12.00	13.00	16.00	23.00
3'-dA	3'	410.00	450.00	455.00	715.00
	int	410.00	450.00	455.00	715.00
	5'	410.00	450.00	455.00	715.00
3'-dC	3'	410.00	450.00	455.00	715.00
	int	410.00	450.00	455.00	715.00
	5'	410.00	450.00	455.00	715.00
3'-dG	3'	410.00	450.00	455.00	715.00
	int	410.00	450.00	455.00	715.00
	5'	410.00	450.00	455.00	715.00
3'-dT	3'	410.00	450.00	455.00	715.00
	int	410.00	450.00	455.00	715.00
	5'	410.00	450.00	455.00	715.00
4-thio-dT	3'
	int	293.00	322.00	325.00	455.00
	5'
5-Br-dC	3'
	int	195.00	215.00	234.00	325.00
	5'
5-Bromo dU	3'
	int	91.00	100.00	117.00	208.00
	5'
5-F-dU	3'	117.00	129.00	143.00	455.00	Less than 3 (Set-up Charge:250.00)
	int	117.00	129.00	143.00	455.00	Less than 3 (Set-upCharge: 250.00)
	5'	117.00	129.00	143.00	455.00	Less than 3 (Set-upCharge: 250.00)
5-Hydroxy-dU	3'
	int	189.00	207.00	228.00	312.00	Less than 3 (Set-upCharge: 250.00)
	5'
5-hydroxymethyl-dC	3'
	int	234.00	257.00	260.00	390.00	Less than 3 (Set-upCharge: 250.00)
	5'
5-hydroxymethyl-dU	3'
	int	189.00	207.00	228.00	312.00	Less than 3 (Set-upCharge: 250.00)
	5'
5'-Nitroindole	3'	163.00	179.00	228.00	325.00
	int	163.00	179.00	228.00	325.00
	5'	163.00	179.00	228.00	325.00
6-thio-dG	3'
	int	293.00	322.00	325.00	455.00
	5'
8-Br-dA	3'
	int	195.00	215.00	234.00	325.00
	5'
8-Br-dG	3'
	int	195.00	215.00	234.00	325.00
	5'
8-Oxo-dA	3'
	int	195.00	215.00	234.00	325.00
	5'
8-Oxo-dG	3'
	int	195.00	215.00	234.00	325.00
	5'
Acridine	3'
	int
	5'	163.00	179.00	228.00	358.00	Less than 3 (Set-upCharge: 250.00)
Acrylamide (acrydite)	3'	117.00	129.00	143.00	455.00
	int
	5'	117.00	129.00	143.00	455.00
AlexaFluor 488	3'	293.00	322.00	325.00	455.00
	int
	5'	293.00	322.00	325.00	455.00
AlexaFluor 647	3'	293.00	322.00	325.00	455.00
	int
	5'	293.00	322.00	325.00	455.00
AMCA (amino-methyl-coumarin-acetate)	3'	163.00	179.00	228.00	358.00	Less than 3 (Set-up Charge:175.00)
	int
	5'	163.00	179.00	228.00	358.00	Less than 3 (Set-up Charge:175.00)
AminoOxy	3'
	int
	5'	163.00	179.00	195.00	286.00
Ara-dC	3'	117.00	129.00	143.00	455.00	Less than 3 (Set-up Charge:250.00)
	int	117.00	129.00	143.00	455.00	Less than 3 (Set-up Charge:250.00)
	5'	117.00	129.00	143.00	455.00	Less than 3 (Set-up Charge:250.00)
Azide	3'	195.00	215.00	228.00	358.00
	int	195.00	215.00	228.00	358.00
	5'	195.00	215.00	228.00	358.00
Azobenzene	3'	163.00	179.00	228.00	325.00
	int	163.00	179.00	228.00	325.00
	5'	163.00	179.00	228.00	325.00
BHQ1	3'	163.00	179.00	195.00	286.00
	int
	5'	234.00	257.00	286.00	429.00
BHQ2	3'	163.00	179.00	195.00	286.00
	int
	5'	234.00	257.00	286.00	429.00
BHQ1-dT	3'
	int	358.00	393.00	390.00	494.00
	5'
BHQ2-dT	3'
	int	520.00	572.00	585.00	910.00
	5'
Biotin	3'	85.00	93.00	104.00	182.00
	int
	5'	52.00	57.00	65.00	156.00
Biotin-TEG	3'	117.00	129.00	143.00	195.00
	int	117.00	129.00	143.00	195.00
	5'	117.00	129.00	143.00	195.00
BromoHexyl (Br)	3'
	int
	5'	195.00	215.00	228.00	358.00
C12 spacer	3'	65.00	72.00	78.00	104.00
	int	65.00	72.00	78.00	104.00
	5'	65.00	72.00	78.00	104.00
C12-Amine	3'
	int
	5'	98.00	107.00	117.00	163.00
C2 Aldehyde	3'
	int
	5'	293.00	322.00	325.00	455.00
C3-Amine	3'
	int
	5'	65.00	72.00	78.00	104.00
C6 Amine	3'	39.00	43.00	52.00	78.00
	int
	5'	26.00	29.00	39.00	65.00
C6 spacer	3'	65.00	72.00	78.00	104.00
	int	65.00	72.00	78.00	104.00
	5'	65.00	72.00	78.00	104.00
C6-Psoralen	3'
	int
	5'	293.00	322.00	325.00	455.00
C8-Alkyne-dC	3'	195.00	215.00	228.00	358.00
	int	195.00	215.00	228.00	358.00
	5'	195.00	215.00	228.00	358.00
C8-Alkyne-dT	3'	195.00	215.00	228.00	358.00
	int	195.00	215.00	228.00	358.00
	5'	195.00	215.00	228.00	358.00
Cholesterol	3'	117.00	129.00	143.00	455.00
	int
	5'	117.00	129.00	143.00	455.00
Cholesterol-TEG	3'	156.00	172.00	195.00	455.00
	int
	5'	156.00	172.00	195.00	455.00
Cyanine3 dA	3'
	int	325.00	358.00	358.00	546.00
	5'
Cyanine3 dC	3'
	int	325.00	358.00	358.00	546.00
	5'
Cyanine3 dG	3'
	int	325.00	358.00	358.00	546.00
	5'
Cyanine3 dT	3'
	int	293.00	322.00	325.00	455.00
	5'
Cyanine5 dA	3'
	int	325.00	358.00	358.00	546.00
	5'
Cyanine5 dC	3'
	int	325.00	358.00	358.00	546.00
	5'
Cyanine5 dG	3'
	int	325.00	358.00	358.00	546.00
	5'
Cyanine5 dT	3'
	int	293.00	322.00	325.00	455.00
	5'
Cyanine3	3'	195.00	215.00	228.00	325.00
	int
	5'	195.00	215.00	228.00	325.00
Cyanine3.5	3'	293.00	322.00	325.00	455.00
	int
	5'	293.00	322.00	325.00	455.00
Cyanine5	3'	195.00	215.00	228.00	325.00
	int
	5'	195.00	215.00	228.00	325.00
Cyanine5.5	3'	293.00	322.00	325.00	455.00
	int
	5'	293.00	322.00	325.00	455.00
Dabcyl	3'	156.00	172.00	195.00	286.00
	int
	5'	286.00	315.00	325.00	455.00
Dabcyl-dT	3'
	int	410.00	450.00	455.00	715.00
	5'
Deoxy Uridine	3'
	int	12.00	13.00	16.00	23.00
	5'
DBCO	3'	234.00	257.00	286.00	429.00
	int
	5'	234.00	257.00	286.00	429.00
DBCO-TEG	3'
	int
	5'	281.00	309.00	343.00	515.00
Deoxypurine (2'-DeoxyNebu larine)	3'	98.00	107.00	117.00	163.00	Less than 3 (Set-up Charge: 250.00)
	int	98.00	107.00	117.00	163.00	Less than 3 (Set-up Charge: 250.00)
	5'	98.00	107.00	117.00	163.00	Less than 3 (Set-up Charge: 250.00)
Desthiobiotin TEG	3'	195.00	215.00	228.00	358.00
	int	195.00	215.00	228.00	358.00
	5'	195.00	215.00	228.00	358.00
DIG	3'	195.00	215.00	228.00	325.00
	int
	5'	195.00	215.00	228.00	325.00
Dithiol	3'	234.00	257.00	286.00	429.00
	int	234.00	257.00	286.00	429.00
	5'	234.00	257.00	286.00	429.00
DNP (2.4-dinitrophenyl)-TEG	3'	163.00	179.00	228.00	358.00	Less than 3 (Set-up Charge:175.00)
	int	163.00	179.00	228.00	358.00	Less than 3 (Set-up Charge:175.00)
	5'	163.00	179.00	228.00	358.00	Less than 3 (Set-up Charge:175.00)
dSpacer	3'	85.00	93.00	104.00	182.00
	int	85.00	93.00	104.00	182.00
	5'	85.00	93.00	104.00	182.00
EBQ	3'	146.00	161.00	176.00	257.00
	int
	5'
EDTA-C2-dT	3'	156.00	172.00	195.00	358.00	Less than 3 (Set-up Charge:250.00)
	int	156.00	172.00	195.00	358.00	Less than 3 (Set-up Charge:250.00)
	5'	156.00	172.00	195.00	358.00	Less than 3 (Set-up Charge:250.00)
Epoch Eclips Quencher	3'	293.00	322.00	325.00	455.00
	int	293.00	322.00	325.00	455.00
	5'	293.00	322.00	325.00	455.00
Ferrocene-dT	3'
	int	234.00	257.00	260.00	390.00
	5'
Fluorescein dT	3'
	int	286.00	315.00	325.00	455.00
	5'
FAM	3'	91.00	100.00	117.00	208.00
	int
	5'	91.00	100.00	117.00	208.00
GalNac	3'
	int
	5'	546.00	601.00	601.00	910.00
HEX	3'
	int
	5'	117.00	129.00	143.00	390.00
HEX-dT	3'
	int	325.00	358.00	358.00	501.00
	5'
Hexynyl	3'
	int
	5'	78.00	86.00	91.00	130.00
Internal Amino Modifier C6 dT	3'
	int	195.00	215.00	234.00	325.00
	5'
Internal Biotin-dT	3'
	int	234.00	257.00	260.00	390.00
	5'
Inverted dA	3'	59.00	64.00	78.00	124.00
	int
	5'
Inverted dC	3'	59.00	64.00	78.00	124.00
	int
	5'
Inverted dG	3'	59.00	64.00	78.00	124.00
	int
	5'
Inverted dT	3'	59.00	64.00	78.00	124.00
	int
	5'
JOE	3'
	int
	5'	234.00	257.00	286.00	429.00
LNA A	3'	65.00	72.00	98.00	163.00
	int	65.00	72.00	98.00	163.00
	5'	65.00	72.00	98.00	163.00
LNA C	3'	65.00	72.00	98.00	163.00
	int	65.00	72.00	98.00	163.00
	5'	65.00	72.00	98.00	163.00
LNA G	3'	65.00	72.00	98.00	163.00
	int	65.00	72.00	98.00	163.00
	5'	65.00	72.00	98.00	163.00
LNA T	3'	65.00	72.00	98.00	163.00
	int	65.00	72.00	98.00	163.00
	5'	65.00	72.00	98.00	163.00
Maleimide	3'	65.00	72.00	85.00	124.00
	int
	5'	65.00	72.00	85.00	124.00
Marina blue	3'	163.00	179.00	228.00	325.00
	int
	5'	163.00	179.00	228.00	325.00
Methylene Blue	3'	234.00	257.00	286.00	429.00	Less than 3 (Set-up Charge: 250.00)
	int	293.00	322.00	325.00	429.00	Less than 3 (Set-up Charge: 250.00)
	5'	234.00	257.00	289.00	429.00	Less than 3 (Set-up Charge: 250.00)
N3-Methyl dC	3'	195.00	215.00	228.00	358.00
	int	195.00	215.00	228.00	358.00
	5'	195.00	215.00	228.00	358.00
N4-Methyl dC	3'	195.00	215.00	228.00	358.00
	int	195.00	215.00	228.00	358.00
	5'	195.00	215.00	228.00	358.00
N6-methyl-2'-deoxyadenosine	3'	156.00	172.00	195.00	286.00	Less than 3 (Set-up Charge:175.00)
	int	117.00	129.00	143.00	455.00	Less than 3 (Set-up Charge:250.00)
	5'	156.00	172.00	195.00	286.00	Less than 3 (Set-up Charge:175.00)
N6-methyl-2'-adenosine	3'
	int	375.00	475.00	685.00	900.00
	5'
O4-Methyl-dT	3'	98.00	107.00	117.00	163.00
	int	98.00	107.00	117.00	163.00
	5'	98.00	107.00	117.00	163.00
O6-Methyl2'-dG	3'	98.00	107.00	117.00	163.00
	int	98.00	107.00	117.00	163.00
	5'	98.00	107.00	117.00	163.00
OMe-dT	3'
	int
	5'	98.00	107.00	124.00	195.00
PC(photo-cleavable)Linker	3'
	int	156.00	172.00	195.00	358.00	Less than 3 (Set-up Charge:250.00)
	5'
PC(photo-cleavable)Amine Linker	3'
	int
	5'	156.00	172.00	195.00	358.00	Less than 3 (Set-up Charge:250.00)
PC(photo-cleavable)Biotin Linker	3'
	int
	5'	156.00	172.00	195.00	358.00	Less than 3 (Set-up Charge:250.00)
Perylene-dU	3'	195.00	215.00	228.00	358.00
	int	195.00	215.00	228.00	358.00
	5'	195.00	215.00	228.00	358.00
Phosphate	3'	39.00	43.00	52.00	78.00
	int
	5'	26.00	29.00	39.00	65.00
Phosphorothioate	3'
	int	4.00	4.00	6.00	10.00
	5'
Puromycine	3'	163.00	179.00	195.00	390.00
	int
	5'
Pyrene-Cap	3'
	int
	5'	293.00	322.00	325.00	455.00
Pyrene-dU	3'	195.00	215.00	228.00	358.00
	int	195.00	215.00	228.00	358.00
	5'	195.00	215.00	228.00	358.00
Rhodamine 6G	3'	293.00	322.00	325.00	455.00
	int
	5'	293.00	322.00	325.00	455.00
ROX	3'	234.00	257.00	286.00	429.00
	int
	5'	234.00	257.00	286.00	429.00
TAMRA	3'	156.00	172.00	195.00	286.00
	int
	5'	156.00	172.00	195.00	286.00
Tamra-dT	3'
	int	286.00	315.00	325.00	455.00
	5'
TET	3'
	int
	5'	163.00	179.00	195.00	390.00
Texas Red	3'	234.00	257.00	286.00	429.00
	int
	5'	234.00	257.00	286.00	429.00
Thiol	3'	195.00	215.00	234.00	325.00
	int
	5'	163.00	179.00	195.00	286.00
Thiol-dT	3'
	int	293.00	322.00	325.00	455.00
	5'
Thymidine Glycol	3'	195.00	215.00	228.00	358.00	Less than 3 (Set-up Charge:175.00)
	int	195.00	215.00	228.00	358.00	Less than 3 (Set-up Charge:175.00)
	5'	195.00	215.00	228.00	358.00	Less than 3 (Set-up Charge:175.00)
Trebler Branching	3'
	int	286.00	315.00	325.00	455.00
	5'
5-Methyl rC	3'
	int	150.00	187.500	275.00	357.500
	5'
5-methyl rU	3'
	int	225.00	262.500	375.00	562.500
	5'
Deoxy Inosine	3'
	int	25.00	30.00	40.00	50.00
	5'
N1-methyladenosine	3'
	int	350.00	410.00	580.00	870.00
	5'
Pseudouridine	3'
	int	350.00	375.00	500.00	750.00
	5'
Ribose-Inosine	3'
	int	10.00	12.500	25.00	75.00
	5'
Triphosphate	3'
	int
	5'	618.00	679.00	780.00	878.00
Yakima Yellow	3'	156.00	172.00	195.00	358.00	Less than 3 (Set-up Charge:250.00)
	int
	5'	325.00	358.00	358.00	455.00	Less than 3 (Set-up Charge:250.00)
Zebularine	3'	98.00	107.00	117.00	163.00	Less than 3 (Set-up Charge:250.00)
	int	98.00	107.00	117.00	163.00	Less than 3 (Set-up Charge:250.00)
	5'	98.00	107.00	117.00	163.00	Less than 3 (Set-up Charge:175.00)
Folic Acid	3'
	int
	5'	315.00	350.00	525.00	680.00
rSpacer	3'	125.00	220.00	250.00	340.00
	int	125.00	220.00	250.00	340.00
	5'	125.00	220.00	250.00	340.00

*For other inquiries, please contact Bioneer technical staff.

DBG: